BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

Location:	District of Columbia
Posted:	Mar 24, 2026
Due:	Apr 15, 2026
Agency:	HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Type of Government:	Federal
Category:	A - Research and development
Solicitation No:	ARPA-H-SOL-26-149
Publication URL:	To access bid details, please log in.

Active

Contract Opportunity

Notice ID

ARPA-H-SOL-26-149

Related Notice

Department/Ind. Agency

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Sub-tier

NATIONAL INSTITUTES OF HEALTH

Office

ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

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General Information View Changes

Contract Opportunity Type: Solicitation (Updated)
Updated Published Date: Mar 24, 2026 12:13 pm EDT
Original Published Date: Jan 30, 2026 12:00 pm EST
Updated Date Offers Due: Apr 15, 2026 12:00 pm EDT
Original Date Offers Due: Apr 15, 2026 12:00 pm EDT
Inactive Policy: 15 days after date offers due
Updated Inactive Date: Apr 30, 2026
Original Inactive Date: Apr 30, 2026
Initiative:
- None

Classification

Original Set Aside: No Set aside used
Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
NAICS Code:
- 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Place of Performance:
Washington , DC

USA

Description View Changes

24 March 2026 Update: This update replaces the original cost proposal spreadsheet (Appendix F) with one that incorporates the ISO's multi-party teaming terminology.

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All questions submitted to the ISO will be compiled and addressed. All answers will be posted to the BIOGAMI Frequently Asked Questions (FAQ) page. Potential proposers are encouraged to monitor the FAQs page regularly for the latest information and updates: https://arpa-h.gov/explore-funding/programs/biogami/faqs

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The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) in support of the BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement.

Interested parties are invited to review the attached BIOGAMI_ISO_ARPA-H-SOL-26-149 and its Appendices A - J.

Additionally, proposers are encouraged to review the separate Special Notice, ARPA-H-SN-26-147, for information regarding the BIOGAMI Proposers’ Day. Special Notice, ARPA-H-SN-26-147, is an independent announcement and is not attached to this ISO announcement.

Attachments/Links

Contact Information

Contracting Office Address

1301 K Street NW Suite 1200 West
Washington , DC 20005
USA

Primary Point of Contact

The BIOGAMI Team
BIOGAMI@arpa-h.gov

Secondary Point of Contact

History

Mar 24, 2026 12:13 pm EDTSolicitation (Updated)
Feb 17, 2026 07:58 pm EST Solicitation (Updated)
Jan 30, 2026 12:00 pm EST Solicitation (Original)

Feb 1, 2026	[Solicitation (Original)] BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)
Feb 18, 2026	[Solicitation (Updated)] BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

Related Document

See also