BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

Location: District of Columbia
Posted: Feb 18, 2026
Due: Apr 15, 2026
Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Type of Government: Federal
Category:
  • A - Research and development
Solicitation No: ARPA-H-SOL-26-149
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BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)
Active
Contract Opportunity
Notice ID
ARPA-H-SOL-26-149
Related Notice
Department/Ind. Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier
NATIONAL INSTITUTES OF HEALTH
Office
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
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General Information View Changes
  • Contract Opportunity Type: Solicitation (Updated)
  • Updated Published Date: Feb 17, 2026 07:58 pm EST
  • Original Published Date: Jan 30, 2026 12:00 pm EST
  • Updated Date Offers Due: Apr 15, 2026 12:00 pm EDT
  • Original Date Offers Due: Apr 15, 2026 12:00 pm EDT
  • Inactive Policy: 15 days after date offers due
  • Updated Inactive Date: Apr 30, 2026
  • Original Inactive Date: Apr 30, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside: No Set aside used
  • Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
    Washington , DC
    USA
Description View Changes

All questions submitted to the ISO will be compiled and addressed. All answers will be posted to the BIOGAMI Frequently Asked Questions (FAQ) page. Potential proposers are encouraged to monitor the FAQs page regularly for the latest information and updates: https://arpa-h.gov/explore-funding/programs/biogami/faqs



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The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) in support of the BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement.



Interested parties are invited to review the attached BIOGAMI_ISO_ARPA-H-SOL-26-149 and its Appendices A - J.



Additionally, proposers are encouraged to review the separate Special Notice, ARPA-H-SN-26-147, for information regarding the BIOGAMI Proposers’ Day. Special Notice, ARPA-H-SN-26-147, is an independent announcement and is not attached to this ISO announcement.


Attachments/Links
Contact Information View Changes
Contracting Office Address
  • 1301 K Street NW Suite 1200 West
  • Washington , DC 20005
  • USA
Primary Point of Contact
Secondary Point of Contact


History

Related Document

Feb 1, 2026[Solicitation (Original)] BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)
Mar 24, 2026[Solicitation (Updated)] BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)
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