Notice of Intent to Sole Source for 10X Genomics, Inc. Reagents Department (CCMD)

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Notice of Intent to Sole Source for 10X Genomics, Inc. Reagents Department (CCMD)

• Product Service Code: 6550


• NAICS Code: 325413


• Place of Performance:

Bethesda, MD 20892

POTS: 25-007194

Description

This is a notice of intent, not a request for a quotation. A solicitation document will not be issued, and quotations will not be requested.

The National Institutes of Health (NIH), Office of Purchasing and Contracts on behalf of the Critical Care Medicine Department (CCMD) intends to award a firm- fixed price Purchase Order to 10X Genomics, Inc, located in Pleasanton, California 94588-3260 on a sole source basis to provide 10X genomics reagents.

The Critical Care Medicine Department (CCMD) is currently conducting a research project focused on investigating the immune response to Pneumocystis infection in murine models, as well as exploring histone modifications to enhance the understanding of Pneumocystis biology. The study utilizes 10X Genomics 5’ v3 Single Cell Sequencing Kits, BCR Amplification Kits, and Single Cell Multiome ATAC + Gene Expression Kits. These proprietary kits contain specialized reagents designed for the isolation and amplification of uniquely barcoded ribonucleic acid (RNA) and chromatin-accessible regions from individual cells.

The advantages of this technology have been repeatedly validated through peer-reviewed studies. To ensure experimental accuracy and maintain compatibility with the existing 10X Genomics instrumentation within CCMD, it is essential to use only genuine 10X Genomics reagents, consumables, and components. The use of non-proprietary or incompatible materials may compromise equipment functionality and result in erroneous data. Therefore, to preserve research continuity and data integrity, it is critical to procure 10X Genomics reagents exclusively.

The below items are required for this action:

Description/Product Code/Quantity:

Chromium Single Cell Mouse BCR Amplification Kit, 16 rxns / Product code: 1000255 QTY: 1

GEM-X Universal 5' Gene Expression v3, 4 samples / Product Code: 1000695 QTY: 3

Chromium GEM-X Single Cell 5' Chip Kit v3, 4 chips / Product Code: 1000698 QTY 1

Library Construction Kit C, 16 rxns / Product Code: 1000694 QTY: 1

Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, 4

Rxns / Product Code: 1000285 QTY: 3

Chromium Next GEM Chip J Single Cell Kit, 16 rxns / Product Code: 1000230 QTY: 2

Dual Index Kit TT Set A, 96 rxn / Product Code: 1000215 QTY: 1

10X Genomics, Inc. is the sole manufacturer of the proprietary reagents required for this procurement.

This acquisition is being conducted using policies unique to the Federal Acquisition Regulation (FAR) Part 13 – Simplified Acquisition Procedures, Subpart 13.106-1(b)(1), For purchases not exceeding the simplified acquisition threshold (SAT), contracting officers may solicit from one source if the contracting officer determines that the circumstance of the contract action deem only one source reasonably available. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements.

Interested Parties:

Interested parties capable of providing the same or similar products or services described in this notice may submit a capability statement outlining their capability to perform the described work. Capability Statements must be received within the time set forth in this synopsis to be considered by the Government. The determination to compete this proposed contract based on responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement.

Comments:

Comments to this announcement, referencing this posting number on the email subject line, may be submitted to the CC, Office of Purchasing and Contracts, prior to the closing date specified in this announcement, electronically to the attention of Tasha Lowe Contract Specialist, lowet2@mail.nih.gov by the due date June 15, 2025, (3:00 pm EST) and time marked in this notice.

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