Renewal of licensing fee for the transgenic mouse strain, B-hIL2RA
| Location: | Maryland |
|---|---|
| Posted: | May 28, 2026 |
| Due: | Jun 8, 2026 |
| Agency: | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
| Type of Government: | Federal |
| Category: | |
| Solicitation No: | 75N98026Q00467 |
| Publication URL: | To access bid details, please log in. |
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- Contract Opportunity Type: Presolicitation (Original)
- Original Published Date: May 28, 2026 04:30 pm EDT
- Original Response Date: Jun 08, 2026 09:00 am EDT
- Inactive Policy: Manual
- Original Inactive Date: Jun 08, 2026
-
Initiative:
- None
- Original Set Aside: No Set aside used
- Product Service Code: 7A21 - IT AND TELECOM - BUSINESS APPLICATION SOFTWARE (PERPETUAL LICENSE SOFTWARE)
-
NAICS Code:
- 51321 - Software Publishers
-
Place of Performance:
MD 20892USA
The MIB is conducting pre-clinical research on photoimmunotherapy (PIT), a targeted treatment approach that uses light activation to destroy specific cells. One area of this research focuses on IL2RA, a protein expressed on regulatory T cells (Tregs). These cells can reduce the immune system’s ability to respond effectively to cancer. The objective of this work is to selectively eliminate IL2RA-expressing Tregs in order to improve anti-cancer immune responses.
To support this research, MIB uses a transgenic mouse strain known as B-hIL2RA, which expresses the human form of IL2RA rather than the mouse form. Use of this model is essential because it enables evaluation of the same treatment materials, including antibodies, that are intended for future human application. As a result, this mouse strain has proven invaluable in the MIB’s ongoing research program.
The MIB is requesting to renew a licensing fee for transgenic mice, B-hIL2RA. B-hIL2RA transgenic mice.
- 6011 EXECUTIVE BLVD., SUITE 503L
- BETHESDA , MD 20892
- USA
- John Burton
- burtonjo@mail.nih.gov
- May 28, 2026 04:30 pm EDTPresolicitation (Original)
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