| Location: | Texas |
|---|---|
| Posted: | May 26, 2026 |
| Due: | May 28, 2026 |
| Agency: | DEPT OF DEFENSE |
| Type of Government: | Federal |
| Category: |
|
| Solicitation No: | N0018926QB059 |
| Publication URL: | To access bid details, please log in. |
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The preclinical development of Cap-dependent endonuclease inhibitors (CENi), a class of small molecules, as broad-spectrum antiviral therapeutics. The scope of this project includes all activities required to select lead CENi candidates, including in vitro and in vivo efficacy studies and characterization and optimization of lead compounds. This includes Research Support expertise regarding the preclinical development of cap-dependent endonuclease inhibitors (CENis) with viruses that require biosafety level 4 (BSL-4) containment to support the Naval Medical Research Command in Fort Detrick, MD. This work will be performed over a 36-month period.
| May 15, 2026 | [Combined Synopsis/Solicitation (Original)] Cap-dependent endonuclease inhibitors (CENis) - NHRC |

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