Screen the A10 antibody for off-target binding to plasma membrane proteins and secreted proteins
| Location: | Federal |
|---|---|
| Posted: | Feb 6, 2026 |
| Agency: | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
| Type of Contract: | Awards |
| Type of Government: | Federal |
| Category: |
|
| Solicitation No: | 75N91026P00004 |
| Publication URL: | To access bid details, please log in. |
- Contract Award Date: Jan 27, 2026
- Contract Award Number: 75N91026P00004
- Task/Delivery Order Number:
- Contractor Awarded Unique Entity ID: KWY4CPWDFNT6
- Contractor Awarded Name: CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED
- Contractor Awarded Address: Saffron Walden CB10 1XL GBR
- Base and All Options Value (Total Contract Value): $38,750.00
- Contract Opportunity Type: Award Notice (Original)
- Original Published Date: Feb 06, 2026 10:02 am EST
- Inactive Policy: 15 days after contract award date
- Original Inactive Date: Feb 11, 2026
-
Initiative:
- None
- Original Set Aside: No Set aside used
- Product Service Code: 6640 - LABORATORY EQUIPMENT AND SUPPLIES
-
NAICS Code:
- 541380 - Testing Laboratories and Services
-
Place of Performance:
Saffron , GB-ESSGBR
This is a Firm Fixed Priced purchase order. NCI solicited and negotiated directly with Charles River Discovery Research Services UK Limited. The National Cancer Institute (NCI) has a program to use an antibody called, 'A10' to target cancer cells that have a lot of the epidermal growth factor receptor on their cell surface. While this antibody has been extensively tested and characterized it is not known if it also binds any other cell surface proteins. The contractor shall perform an off-target screen on an NCI antibody and report back on any problematic interactions that could predict a serious side effect should the antibody be given to a cancer patient. The A10 is NOT known to bind other cell surface proteins or secreted proteins but this needs to be addressed in the off-target screen.
- 12501 ARDENNES AVE. SUITE 400
- ROCKVILLE , MD 20857
- USA
- Elizabeth Bulger
- elizabeth.bulger@hhs.gov
- Feb 06, 2026 10:02 am ESTAward Notice (Original)
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