National Amyotrophic Lateral Sclerosis (ALS) Biorepository’s Augmentation of ALS Samples for Researchers through an Established External Repository

The Centers for Disease Control and Prevention intends to award a sole source firm fixed price contract to Temple University ALS Postmortem Core to provide National Amyotrophic Lateral Sclerosis (ALS) Biorepository’s Augmentation of ALS Samples for Researchers through an Established External Repository. The Government seeks to identify a nationally recognized tissue core repository for the purpose of advancing ALS research in the areas of risk factors, genetics, biomarkers, and identification of etiologies via the dissemination and collection of ALS samples. The anticipated period of performance is 05/01/2026 through 04/30/2027 and will include four one-year option periods. This contract action is for services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.103-1 and 41 U.S.C. § 3304(a)(1). The procedures in FAR 12.201-1 will be used in accordance with 41 U.S.C. § 1901. Interested contractors may identify their interest and capability to respond to the requirement or submit proposals. If an interested party does not provide enough information to determine capability, their response will not be considered.

The Government requires a nationally recognized center for high quality ALS samples for

researchers. The contractor must have extensive experience of facilitating and providing tissue samples and data to facilitate different ALS research projects in academic and industry laboratories worldwide.

The contractor must have a repository compromised of:

Frozen and fixed CNS tissues, liver, and several muscles from ALS/MND and non-neurologic control autopsies. A limited number of other tissues (sural/sciatic nerve, GI tract, skin, etc.) are also available.

Standard Operating Procedures for tissue dissection, processing, QC analysis, clinical data elements, and neuropathological characterization are specifically optimized to meet the needs of ALS researchers.

A dissection method that produces the maximum number of individual, optimally sized tissue samples from each ALS-relevant region, while preserving the architecture of the tissue.

A large collection of ALS samples from the Guam cluster which was recognized as major public health emergency.

This notice of intent is not a request for competitive quotations; however, all quotations/responses received prior to the date and time below will be considered by the government. A determination by the government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to the Contracting Officer at xur0@cdc.gov by 1:00PM (ET) on 4/7/2026.