6640--Sioux Falls Health Care System - Brand Name or Equal Supply Procurement of DORIC Fiber Photometry System

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The Sioux Falls Health Care System requires the purchase of a Fiber Light Source & Photometry Console with the salient characteristics listed below.

This is a SOURCES SOUGHT NOTICE only looking for American manufactured equipment as listed below for market research purposes. No proposals are being requested or accepted with this notice. THIS IS NOT A SOLICITATION FOR PROPOSALS OR PRICING AND NO CONTRACT SHALL BE AWARDED FROM THIS NOTICE. This notice shall not be construed as a solicitation or as an obligation on the part of the Department of Veterans Affairs.
The Buy American Act, FAR 52.225-1, applies. Interested vendors shall include the place of manufacture in their responses.
Responses to this notice will be treated only as information for the Government to consider as part of their market research efforts. The information provided will be used by the Government in developing its acquisition strategy regarding possible set aside for Veteran Owned and other socio-economic categories of small business. Interested parties are responsible for adequately marking proprietary, restricted or competition sensitive information contained in their response. The Government does not intend to pay for the information submitted in response to this notice and parties responding will not be entitled to payment for direct or indirect costs incurred in responding to this notice.
The North American Industry Classification System (NAICS) code for this requirement is 334516 Surgical Appliance and Supplies Manufacturing with an SBA Small Business Size Standard of 1,000 employees.
The deadline for this information is 4:00 PM Central Time on Thursday, December 19, 2025.

(Functional/Performance/Specification (Brand Name or Equal))
This requirement includes meeting Brand Name or equal to the DORIC Fiber Photometry system. The system includes Behavior & Bundle Photometry Console (BBC300), Fiber Photometry with Fluorescence Mini Cubes, Fiber Photometry with Rotary Fluorescence Mini Cube, Bundle-imaging Fiber Photometry, Wireless Photometry, Rotary Bundle-imaging Fiber Photometry, FluoPulse system, Doric Neuroscience Studio V6 software, Danse software, and Fiber Photometry Accessories.

Fiber photometry monitors neuronal activity in the brain of freely moving behaving animals that helps correlate brain functioning with animal behavior. It uses implanted fiber-optic cannula to deliver excitation light to a group of neurons labeled with genetically encoded calcium indicators and detect their calcium-related fluorescence fluctuations. While it lacks the cellular/spacial resolution of a miniature fluorescence microscope, fiber photometry uses a relatively simple setup to record fluctuations in the calcium activity of a group of neurons in behaving animals. A smaller cannula's fiber diameter is better suited for deep tissue neuronal activity monitoring than a somewhat larger lens of miniature fluorescence microscopes.

Optogenetics uses light to control the activity of specific neurons that have been genetically modified to express light sensitive proteins. Allows researchers to turn neurons on or off based on cell type, enabling causal investigation of neural circuit function. Used to test the role of specific neural pathways in complex behaviors like aggression, anxiety, and sleep. Allows for precise control over when and where neural activity is manipulated.

Integrating fiber photometry and optogenetics using specialized software allows for simultaneous recording of neural activity and optogenetic stimulation in freely moving animals. Allows researchers to correlate specific neural activity patterns with specific behaviors. Enables the design of more complex and comprehensive experiments to probe neural circuits.

Sioux Falls VA Health Care System requires the following:

QTY 1: Behavior & Bundle Photometry Console
Must have at least 4 x USB 3.0 ports
Must have at least 4 x Camera Trigger ports
Must have at least 4 x Analog Outputs (for light source control)
Must have at least 8 x Digital Input/Output (DIO) ports
Must have at least 24 additional Digital ports (8x inputs/outputs, 8x inputs, 8x outputs) with the extension board

QTY 1: 4 laser diodes Fiber Light Source - 4x 638nm - 80 mW, LDFLS-4CH and 4x 450nm - 75 mW, LDFLS-4CH
Must meet the following laser diode and fiber light criteria:
Optical Fiber: Multimode 50 m
Power stability: TTL Modulation: HI > 2.8 V, LOW Analog Modulation: 0 - 5 V (80 mA / V and 75mA/ V)
Rise / Fall time: Max modulation frequency: 10 kHz

QTY 4: Mono Fiberoptic Patchcord, MFP_200/220/LWMJ-0.22_1m_FC-FCA
Must meet the following Fiber-optic capability: 200/220/900-0.37 or Core ( m): 200, Cladding ( m): 220, Buffer: 245, Jacket: 900, NA: 0.37

QTY 1: Branching Box for HD9 pattern - 9 FC inputs, 1 HD9 output
Must have at least 9 input ports
Must be compatible with FC Input Optical Connector
Must be compatible with HD9 Output Optical Connector
Must have the following dimension, 211 x 94 x 45 mm

QTY 1: Bundle-imaging Fiber Photometry Cube with Targeted Optogenetics
Must have a wavelength range of 350 to 1100 nm
Must have a field of view (FOV) of Ø3 mm
Must have an objective numerical aperture (NA) of 0.40
LEDs Excitation Uniformity must be 80% over FOV
Optogenetics Excitation Uniformity must be 65% over FOV
Optogenetics Crosstalk between fibers must be >31 dB
Must have optical fiber compatibility with the following fiber optic core diameter 200 or 400 µm and NA 0.37
Must be able to measure spectral bandwidth within the following 3 excitation and 2 emission ranges:
Excitation #1: 405-410, 410-415, 421-433 or 433-445nm
Excitation #2: 460-490 nm
Excitation #3: 555-570 nm
Emission #1: 500-540 nm
Emission #2: 580-600 nm
Optical filter attenuation must be > Optical Density (OD) 5 outside band
Must be compatible with HD7, HD9 or HD19 Optical fiber connectors.
Dimensions must be 220mm x 220mm x 59mm
Must have a CMOS (Complementary Metal-Oxide Semiconductor) image sensor
Must provide 1024x1024 px resolution
Must provide Pixels size down to 5.86 µm x 5.86 µm
Must have a frame rate up to 60 Hz
Must have a USB 3.0 Computer interface.

QTY 1: High Density Fiberoptic Patch cord - Low Autofluorescence

QTY 8: Ferrule Connector (FC)/Ferrule Connector (FC) Mating Adapter Round

QTY 8: Fiberoptic Rotary Joint, pigtailed with 400 um, NA0.37 fibre, 1.0m input, 0.15m output, optimized for fiber photometry

QTY 8: Gimbal holder for FRJ 1x1_PT-G2 - ID 19 mm
Must have 96 mm x 69 mm x 25 mm dimensions

QTY 8: Mono Fiberoptic Patchcord - Low AutoFluorescence
Must have the following Fiber-Optic Codes to ensure system compatibility
Optical Fiber Type: Silica/Silica
Core: Glass
Cladding: Glass
Numerical Aperture: 0.22-0.37
Flexibility: Good
Auto-Fluorescence: Excellent
Core Diameter ( m): 400
Cladding ( m): 440
Buffer ( m): 470
NA: 0.37
Must have the following Jacket Codes to ensure system compatibility.
Composition Code: 1100
Description: Hytrel loose tube 1.1 mm
Color: Black
OD (mm): 1.1
Linear Mass (g/m): 0.5

Must be compatible with the following Connectors:
1st Connector Code: FCM (Flexible metal conduit)
1st Connector Description: FC Connector with Metal Ferrule
2nd Connector Code: MF1.25(F)
2nd Connector Description: Metal Ferrule OD 1.25 mm with Flange

QTY 10: Zirconia Sleeve 1.25 mm with black cover
Must have a Ferrule Diameter of 1.25mm

QTY 30: Mono Fiberoptic Cannula
Fiber-Optic must be made from Silica/Silica material
Fiber-Optic type must be 400( m) NA 0.37
Fiber Lenth must 5.0mm
Receptacle must be a male to female (MF) 1.25
Fiber tip must be flat (FLT)

QTY 2: Stereotaxic Cannula Holder 1.25 mm
Ferrule diameter must be 1.25mm
Rod diameter must be 6.3 mm

QTY 1: CamLoop with RGB camera and Wide-Angle lens, Behavior tracking System for closed loop stimulation
Must be able to provide 1440 x 1080 px (1.6MP) resolution
Must have dynamic range of 12 bits
Must provide gain range of 0 to 48 dB
Must be able to provide a Frame rate of at least 60 fps at full resolution
Sensor format: 1 / 2.9''
Must have a USB 3.0 Interface
Minimum exposure of 1 ms or less
Lens must be mounted using C-mount or CS-mount

QTY 1: Danse 3-year subscription, Data Analysis Software, 1 license

QTY 1: Gentec-EO Pronto-SI Power Meter + SM1 Treaded adaptor + 2.5mm receptacle + 1.25mm, receptacle

QTY 1: High performance workstation set up for Doric's systems
Must have an Intel Core i9 13th gen. 24-core processor or better
Must have a minimum RAM of 2x32GB DDR5 5600
Must have GeForce RTX 3060 12GB DDR6 or better graphic card to accurately capture and measure video files.
Must have SSD 4TB NVMe + Hard Drive 4TB or better to support the software and system.
Must be Win11 Pro compatible to run the system software.
QTY 1: Assisted 2x2 Fiber-optic Rotary Joint, 400 um NA0.37 fibre, 1m input, optimized for fiber photometry Part # AFRJ_2x2_PT_400-0.37

QTY 1: Base Station for wireless fiber photometry system
Must have a transmission range up to 2 meters
Must be able to accommodate 4 headstages
Must operate within 2.4 - 2.5 GHz wireless frequency band.
Base Station Interface must be compatible with HDMI (to NC500) or USB-B (to BBC300)

QTY 1: Wireless Photometry Headstage - ferrule 2.5 mm - 1 integrated photodetector and 2 integrated LEDs. With a 40mAh battery

QTY 1: Battery Charger for wireless fiber photometry - Part # WiFP_CHRG
Must Interface with a USB-C
Power Supply: 1 meter cable USB-C to USB-A
Must have a capacity of 4 headstages

QTY 10: Multi Fluid Injections Cannulas, OmFC_ZF1.25_400/470-0.37_5.0mm_FLT_4.9mm_PLGS

QTY 10: OmFC Fluid Injector Part # FI_OmFC-ZF_140/190_5.1mm

QTY 10: Mono Fiberoptic Cannula Part # MFC_400/430-0.37_5mm_ZF2.5_FLT

QTY 1: Co-Extruded PE/PVC Tubing for HRJ-OL Part# HRJ-OL _BTCOEX_25Ga_clear (2 meters)

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