ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Location:	Federal
Posted:	Sep 17, 2026
Due:	Oct 7, 2026
Agency:	HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Type of Government:	Federal
Category:	A - Research and development
Solicitation No:	ARPA-H-SOL-26-165
Publication URL:	To access bid details, please log in.

Active

Contract Opportunity

Notice ID

ARPA-H-SOL-26-165

Related Notice

Department/Ind. Agency

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Sub-tier

NATIONAL INSTITUTES OF HEALTH

Office

ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

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General Information View Changes

Contract Opportunity Type: Solicitation (Updated)
Updated Published Date: Sep 17, 2026 11:51 am EDT
Original Published Date: Sep 16, 2026 03:17 pm EDT
Updated Date Offers Due: Oct 07, 2026 02:00 pm EDT
Original Date Offers Due: Oct 07, 2026 02:00 pm EDT
Inactive Policy: 15 days after date offers due
Updated Inactive Date: Oct 22, 2026
Original Inactive Date: Oct 22, 2026
Initiative:
- None

Classification

Original Set Aside:
Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
NAICS Code:
- 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Place of Performance:

Description View Changes

The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth.

ARPA-H anticipates multiple Other Transaction awards resulting from this announcement.

Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165

Amendment 01 – 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal.

Attachments/Links

Contact Information

Contracting Office Address

1301 K Street NW Suite 1200 West
Washington , DC 20005
USA

Primary Point of Contact

COSMOS Team
COSMOS@ARPA-H.GOV

Secondary Point of Contact

History

Sep 17, 2026 11:51 am EDTSolicitation (Updated)
Sep 16, 2026 03:17 pm EDT Solicitation (Original)

Sep 16, 2026	[Solicitation (Original)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 21, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 23, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 25, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Oct 7, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Related Document

See also