Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice
| Location: | Maryland |
|---|---|
| Posted: | Aug 12, 2025 |
| Due: | Aug 18, 2025 |
| Agency: | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
| Type of Government: | Federal |
| Category: |
|
| Solicitation No: | 75N95025Q00237 |
| Publication URL: | To access bid details, please log in. |
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- Contract Opportunity Type: Presolicitation (Original)
- Original Published Date: Aug 12, 2025 06:55 am EDT
- Original Response Date: Aug 18, 2025 12:00 pm EDT
- Inactive Policy: 15 days after response date
- Original Inactive Date: Sep 02, 2025
-
Initiative:
- None
- Original Set Aside: No Set aside used
- Product Service Code: B504 - SPECIAL STUDIES/ANALYSIS- CHEMICAL/BIOLOGICAL
-
NAICS Code:
- 541380 - Testing Laboratories and Services
-
Place of Performance:
Rockville , MD 20850USA
NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity
towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the
therapeutic window for YC1. To that end NCATS requires head-to-head comparison on
YC1 in mice that have humanized SULT1A1 (custom mice available at
GemPharmaTech) and with mouse SULT1A1 (wild type).
- c/o 3WFN MSC 6012 301 N Stonestreet Ave
- Bethesda , MD 20892
- USA
- Andrew Varley
- andrew.varley@nih.gov
- Phone Number 3018275851
- Joshua T. Lazarus
- Josh.Lazarus@nih.gov
- Phone Number 3018276923
- Aug 12, 2025 06:55 am EDTPresolicitation (Original)
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