Intent to Sole Source - 10x Genomics Chromium Single Cell 5' v2 Reagent Kit

This is a Notice of Intent, not a request for proposal. The National Institute of Health intends to negotiate on an other than full and open competition basis with the following vendor: 10X Genomics, Inc.

Acquisition Description:

The National Institutes of Health requires the procurement of the 10X Genomics 5' v2 Kit to support the Early Detection of Lung Diseases (EDLI) project. This kit is a specialized reagent set designed exclusively for the 10X Genomics Chromium platform/instrument, enabling cutting-edge single-cell and multiomic analyses.

The 5' v2 Kit facilitates high-resolution gene expression profiling, immune repertoire analysis, and other advanced applications critical to identifying early biomarkers and understanding the molecular mechanisms of infectious and noninfectious lung diseases. These capabilities are essential to achieving the EDLI project’s objectives, which aim to advance diagnostic and therapeutic strategies for lung health.

This acquisition includes proprietary reagents, consumables, and supporting components optimized for use with the Chromium platform. The compatibility and precision of the 5' v2 Kit are necessary to ensure data integrity, reproducibility, and experimental consistency across ongoing and future studies.

The statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-CC-OLAO-26-005835) by 12:00 PM eastern standard time on 05/21/2026 to: valerie.gregorio@nih.gov.

All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.