Agency: | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
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State: | Montana |
Type of Government: | Federal |
Category: |
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Posted: | Jan 27, 2023 |
Due: | Feb 6, 2023 |
Solicitation No: | NIAID-SS-23-2160376 |
Publication URL: | To access bid details, please log in. |
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Introduction
This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.
Project Summary
The National Institute of Allergy and Infectious Diseases (NIAID), Research Technologies Branch (RTB) is seeking to acquire two Talos 120 kV or equal transmission electron microscopes for performance across a wide range of applications, such as 2D and 3D imaging of cells, cell organelles, and soft materials, both at ambient and cryogenic (liquid-nitrogen) temperatures. Additionally, these microscopes will be used to screen both SARS-CoV2, and other vaccine candidates studied by scientists for on-going structural studies. The microscopes will provide a mechanism for quality assessment and serve as a first step towards evaluating proteins, viruses or bacterial preparations for high resolution imaging on a Titan Krios electron microscope. With high demand for ultrastructural studies by scientists, these microscopes will help evaluate samples not limited to SARS-CoV2 projects. The Talos 120 kV or equal microscopes would also play a crucial role in evaluating recombinant rVSV vaccine candidates, analyzing a replicating RNA lipid-based nanoparticle emulsions, and analyses of the spike protein between SARS variants and SARS-CoV2 micro-clot model systems as some examples. These microscopes will not only help alleviate the bottleneck on the Titan Krios by prescreening these samples but also serve as primary microscopes for all the SARS-CoV2 room temperature tomography projects.
Specifically, NIAID, RTB is seeking two transmission electron microscopes that must include all components and camera system requirements listed below:
Anticipated Period of Performance
It is anticipated that an award will be made on or about March 31, 2023. Delivery of microscopes will be required as soon as possible.
Capability Statement/Information Sought
If your organization has the potential capacity to provide two transmission electron microscopes which meets the minimum requirements and performance capabilities listed above, please provide the following information:
Submission Instructions
Interested businesses who consider themselves qualified to provide the above listed transmission electron microscopes are invited to submit a response to this Sources Sought Notice by February 6, 2023, at 3:00 PM EST. All responses under this Sources Sought Notice shall be emailed to Hershea Vance at hershea.vance@nih.gov.
Disclamer and Important Notes
This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.
Confidentiality
No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
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